DNA夾

DNA夾英語:,又称滑动压板滑行夹)是一種蛋白質三級結構,為DNA複製過程中的持續性-啟動因子(processivity-promoting factor),是DNA聚合酶III全酶的必要組成,可避免DNA聚合酶(DNA polymerase)與DNA模板分離,並提升DNA合成速率。

聚集在一起的人類DNA夾,PCNA蛋白質的三聚體

外部連結

參考文獻

  • Watson JD, Baker TA, Bell SP, Gann A, Levine M, Losick R. (2004). Molecular Biology of the Gene 5th ed. Benjamin Cummings: Cold Spring Harbor Laboratory Press.
  • Gulbis, J.M., Kelman, Z., Hurwitz, J., O`Donnell, M., Kuriyan, J. (1996). Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell 87:297-306.
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