异噻唑
异噻唑(isothiazole),或称1,2-噻唑是一种杂环化合物,化学式C3H3NS。[3]其含有一个氮硫杂五元环,氮原子和硫原子的位置是相邻的。
异噻唑 | |||
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识别 | |||
CAS号 | 288-16-4 | ||
PubChem | 67515 | ||
ChemSpider | 60838 | ||
SMILES |
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InChI |
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InChIKey | ZLTPDFXIESTBQG-UHFFFAOYAS | ||
ChEBI | 35600 | ||
性质 | |||
化学式 | C3H3NS | ||
摩尔质量 | 85.13 g·mol−1 | ||
沸点 | 114 °C(387 K)([1]) | ||
pKa | -0.5 (其共轭酸)) [2] | ||
相关物质 | |||
相关化学品 | 噻唑, 异恶唑 | ||
若非注明,所有数据均出自一般条件(25 ℃,100 kPa)下。 |
异噻唑的环结构见于某些药物,例如例如齐拉西酮。
参考资料
- Isothiazoles, D. W. Brown and M. Sainsbury, page 513
- Zoltewicz, J. A. & Deady, L. W. Quaternization of heteroaromatic compounds. Quantitative aspects. Adv. Heterocycl. Chem. 22, 71-121 (1978).
- Heterocyclic Chemistry, 3rd Edition, J.A. Joule, K. Mills, and G.F. Smith, page 394
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