香菇多糖
香菇多糖[1](英語:)是从香菇(Lentinula edodes)子实体或菌丝中分离的一种多糖,以β-1,3-葡聚糖为主,在6号位碳原子上有支链。透過靜脈注射,有免疫激活和抗肿瘤活性,特別是胃癌[2]。
系统(IUPAC)命名名称 | |
---|---|
β-D-glucopyranosyl-(1→6)-[β-D-glucopyranosyl-(1→3)-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→3)β-D-glucopyranosyl-(1→3)]-β-D-glucopyranose | |
临床数据 | |
Drugs.com | 国际药品名称 |
识别 | |
CAS注册号 | 37339-90-5 |
ATC代码 | L03AX01 |
PubChem | CID 37723 |
ChemSpider | NA |
KEGG | D01695 |
其他名称 | (2S,3R,4S,5S,6R)-2-[(2S,3R,4S,5R,6R)-2-[(2S,3R,4S,5R,6R)-2-[(2R,3R,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3R,4S,5R,6R)-2,3,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-4-yl]oxyoxan-4-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,5-dihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol |
化学 | |
化学式 | C42H72O36 |
摩尔质量 | 1152.99948 g/mol |
参考文献
- Chihara, G. et al. ”Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk.) Sing. (an edible mushroom)”, Cancer Research (1970),30(11):2776-2781. 页面存档备份,存于
- Ina, K. et al. “Lentinan prolonged survival in patients with gastric cancer receiving S-1-based chemotherapy”, World Journal of Clinical Oncology (2011),2(10):339-343.
外部链接
- Lentinan effects (antitumor and others)
- Memorial Sloan-Kettering Cancer Center's page for Lentinan Archive.is的存檔,存档日期2012-12-28.
- About Shiitake (by Solomon P. Wasser, 2005)
- Smith JE, Rowan NJ, Sullivan R Medicinal Mushrooms: Their Therapeutic Properties and Current Medical Usage with Special Emphasis on Cancer Treatments Cancer Research UK, 2001
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