CD132

IL2RG
已知的結構
PDB	Ortholog search: PDBe RCSB
PDBID列表
	2B5I、2ERJ、3BPL、3QAZ、3QB7、4GS7
識別號
别名	IL2RG；CD132、CIDX、IL-2RG、IMD4、P64、SCIDX、SCIDX1、interleukin 2 receptor subunit gamma
外部ID	OMIM：308380 MGI：96551 HomoloGene：172 GeneCards：IL2RG
相關疾病
	X性聯嚴重複合免疫缺乏症[1]
基因本體
分子功能	• interleukin-7 receptor activity; • interleukin-2 receptor activity; • 血浆蛋白结合; • cytokine receptor activity; • interleukin-4 receptor activity; • Ras guanyl-nucleotide exchange factor activity; • interleukin-2 binding; • cytokine binding; • interleukin-15 receptor activity;
細胞組分	• integral component of membrane; • 膜; • 细胞膜; • integral component of plasma membrane; • external side of plasma membrane; • 核内体; • 细胞质基质; • cell surface; • receptor complex;
生物學過程	• MAPK cascade; • 免疫反应; • viral process; • 訊息傳遞; • interleukin-2-mediated signaling pathway; • interleukin-4-mediated signaling pathway; • interleukin-7-mediated signaling pathway; • interleukin-15-mediated signaling pathway; • interleukin-9-mediated signaling pathway; • regulation of molecular function; • cytokine-mediated signaling pathway; • interleukin-21-mediated signaling pathway; • positive regulation of phagocytosis;
	Sources:Amigo / QuickGO
RNA表达模式
	更多參考（基因）表达數據
直系同源
	3561
	16186
	ENSG00000147168
	ENSMUSG00000031304
	P31785
	P34902
	NM_000206
	NM_013563、NM_001308535、XM_017318396
	NP_000197
	NP_001295464、NP_038591、XP_017173885
	維基數據
檢視/編輯人類	檢視/編輯小鼠

CD132，又称为共用γ链（Common gamma chain，缩写γ_c)，白介素2受体γ亚基（interleukin-2 receptor subunit gamma，缩写IL-2RG）是一种细胞因子受体亚基，存在于至少六种不同的白介素受体中：包括IL-2、IL-4[4]、IL-7[5]、IL-9、IL-15[6]和IL-21的受体。γ_c是I型细胞因子受体家族中的一种醣蛋白，表达于大部分的淋巴细胞群体，哺乳动物的此基因位于X染色体。

参考文献

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Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ. . Science. December 1993, 262 (5141): 1877–80. PMID 8266077. doi:10.1126/science.8266077.
Giri JG, Kumaki S, Ahdieh M, Friend DJ, Loomis A, Shanebeck K, DuBose R, Cosman D, Park LS, Anderson DM. . EMBO J. August 1995, 14 (15): 3654–63. PMC 394440. PMID 7641685.

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外部链接

MeSH（醫學主題詞）上面的Interleukin+Receptor+Common+gamma+Subunit（美式英语）

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[1] .

[2] .

[3] .

[pmid8266078-4] Russell SM, Keegan AD, Harada N, Nakamura Y, Noguchi M, Leland P, Friedmann MC, Miyajima A, Puri RK, Paul WE. . Science. December 1993, 262 (5141): 1880–3. PMID 8266078. doi:10.1126/science.8266078.

[pmid8266077-5] Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ. . Science. December 1993, 262 (5141): 1877–80. PMID 8266077. doi:10.1126/science.8266077.

[pmid7641685-6] Giri JG, Kumaki S, Ahdieh M, Friend DJ, Loomis A, Shanebeck K, DuBose R, Cosman D, Park LS, Anderson DM. . EMBO J. August 1995, 14 (15): 3654–63. PMC 394440. PMID 7641685.