細胞色素c

細胞色素c，體細胞
	血紅素及細胞色素c
有效结构
PDB	直系同源检索：PDBe, RCSB
PDB查询代码列表
	1j3s, 2b4z
标识
代号	CYCS; HCS; CYC
扩展标识	遗传学：123970 鼠基因：88578 同源基因：68675 GeneCards: CYCS Gene
基因本体论描述
分子功能	· protein phosphatase type 2A activity; · iron ion binding; · protein binding; · heme binding; · electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; · metal ion binding;
细胞成分	· protein phosphatase type 2A complex; · nucleus; · mitochondrion; · mitochondrial respiratory chain; · mitochondrial intermembrane space; · cytosol;
生物过程	· electron transport; · DNA fragmentation during apoptosis; · transport; · apoptosis; · caspase activation via cytochrome c; · cellular respiration;
	Sources: Amigo / QuickGO
RNA表达模式
	更多表达数据
直系同源体

細胞色素c（英語：）或稱細胞色素複合體（英語：），是一種血紅素蛋白，屬於cytochrome c family。細胞色素c會與粒線體內膜輕微連接，結構鬆散而微小的它和其他細胞色素不同，是一種高度可溶性蛋白，在水中的可溶性達每公升100克。細胞色素c是電子傳遞鏈不可或缺的元件，負責攜帶一粒電子，在複合物III和複合物IV之間傳遞。此外，它能夠接受氧化和還原反應，但不與氧結合。在人體中，細胞色素c已經由CYCS基因完成編碼[1][2]。

細胞色素c和細胞程序性死亡有關[3]。

交互作用

細胞色素c被證實會和COX4I2進行交互作用[4][5][6][7]。

參考資料

. NCBI. 2011-06-18 （英语）.
Marco Tafani, Natalie O. Karpinich, Kathryn A. Hurster, John G. Pastorino, Timothy Schneider, Matteo A. Russo, John L. Farber. . The Journal of Biological Chemistry. 2002-03-22, 277 (12): 10073–10082 [2019-05-25]. ISSN 0021-9258. PMID 11790791. doi:10.1074/jbc.M111350200.
. 國立陽明大學生命科學院. [2011-07-02]. （原始内容存档于2012-01-10）.
Michel, B; Bosshard H R. . J. Biol. Chem. (UNITED STATES). Aug 1984, 259 (16): 10085–91. ISSN 0021-9258. PMID 6088481 （英语）.
Wiedemann, F R; Vielhaber S, Schröder R, Elger C E, Kunz W S. . Anal. Biochem. (UNITED STATES). Mar 2000, 279 (1): 55–60. ISSN 0003-2697. PMID 10683230. doi:10.1006/abio.1999.4434 （英语）.
Sampson, V; Alleyne T. . Eur. J. Biochem. (Germany). Dec 2001, 268 (24): 6534–44. ISSN 0014-2956. PMID 11737208. doi:10.1046/j.0014-2956.2001.02608.x （英语）.
Lynch, S R; Sherman D, Copeland R A. . J. Biol. Chem. (UNITED STATES). Jan 1992, 267 (1): 298–302. ISSN 0021-9258. PMID 1309738 （英语）.

延伸閱讀

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其他圖像

ETC

外部連結

細胞色素c蛋白（英文）
細胞凋亡 & Caspase-3 蛋白酶 - PMAP 蛋白酶動畫（英文）* Template:UMichOPM - Calculated orientations of cytochromes c in the lipid bilayer
MeSH（醫學主題詞）上面的Cytochrome+c（美式英语）（英文）

Template:Fas apoptosis signaling pathway

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[entrez-1] . NCBI. 2011-06-18 （英语）.

[pmid11790791-2] Marco Tafani, Natalie O. Karpinich, Kathryn A. Hurster, John G. Pastorino, Timothy Schneider, Matteo A. Russo, John L. Farber. . The Journal of Biological Chemistry. 2002-03-22, 277 (12): 10073–10082 [2019-05-25]. ISSN 0021-9258. PMID 11790791. doi:10.1074/jbc.M111350200.

[3] . 國立陽明大學生命科學院. [2011-07-02]. （原始内容存档于2012-01-10）.

[pmid6088481-4] Michel, B; Bosshard H R. . J. Biol. Chem. (UNITED STATES). Aug 1984, 259 (16): 10085–91. ISSN 0021-9258. PMID 6088481 （英语）.

[pmid10683230-5] Wiedemann, F R; Vielhaber S, Schröder R, Elger C E, Kunz W S. . Anal. Biochem. (UNITED STATES). Mar 2000, 279 (1): 55–60. ISSN 0003-2697. PMID 10683230. doi:10.1006/abio.1999.4434 （英语）.

[pmid11737208-6] Sampson, V; Alleyne T. . Eur. J. Biochem. (Germany). Dec 2001, 268 (24): 6534–44. ISSN 0014-2956. PMID 11737208. doi:10.1046/j.0014-2956.2001.02608.x （英语）.

[pmid1309738-7] Lynch, S R; Sherman D, Copeland R A. . J. Biol. Chem. (UNITED STATES). Jan 1992, 267 (1): 298–302. ISSN 0021-9258. PMID 1309738 （英语）.