SH3结构域

SH3结构域英語:,全称Src同源3结构域英語:)是最早在病毒接头蛋白v-Crk及酪氨酸激酶SrcAbl中发现的长约60个氨基酸残基的保守结构域[1][2],在磷酸肌醇3-激酶Ras超家族G蛋白cdc25中也存在[3][4][5]

SH3 domain
α-血影蛋白的SH3结构域的飘带图,PDB代码1SHG,N-端为蓝色,C-端为红色
鑑定
標誌SH3_1
PfamPF00018
Pfam宗系CL0010
InterProIPR001452
SMARTSM00326
PROSITEPS50002
 SCOP1shf / SUPFAM
CDDcd00174

参考文献

  1. Pawson T, Schlessingert J. . Current Biology. July 1993, 3 (7): 434–42. PMID 15335710. doi:10.1016/0960-9822(93)90350-W.
  2. Mayer BJ. . Journal of Cell Science. April 2001, 114 (Pt 7): 1253–63. PMID 11256992. doi:  请检查|doi=值 (帮助).
  3. Musacchio A, Gibson T, Lehto VP, Saraste M. . FEBS Letters. July 1992, 307 (1): 55–61. PMID 1639195. doi:10.1016/0014-5793(92)80901-R.
  4. Mayer BJ, Baltimore D. . Trends in Cell Biology. January 1993, 3 (1): 8–13. PMID 14731533. doi:10.1016/0962-8924(93)90194-6.
  5. Pawson T. . Nature. February 1995, 373 (6515): 573–80. PMID 7531822. doi:10.1038/373573a0.

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