群孕酮
群孕酮(英語:,商品名为Reteroid、Retroid或Retrone)是一种黄体制剂药物,曾经用于治疗月经失调,但现已不再使用[2][3][4][5][6]
系统(IUPAC)命名名称 | |
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(8S,9S,10R,13S,14S,17S)-17-acetyl-6-chloro-10,13-dimethyl-8,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-3-one | |
临床数据 | |
商品名 | Reteroid, Retroid, Retrone |
给药途径 | By mouth |
合法狀態 | |
合法状态 |
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药代动力学数据 | |
生物利用度 | ≥41–46% (based on urinary excretion)[1] |
代谢 | Liver |
代謝產物 | • 20α-Dihydrotrengestone[1] |
生物半衰期 | • Trengestone: very short[1] • 20α-DHTG: 8–14 hours[1] |
排泄 | Urine: 41–46%[1] Feces: 30% (unchanged)[1] |
识别 | |
CAS注册号 | 5192-84-7 |
ATC代码 | None |
PubChem | CID 56840930 |
ChemSpider | 28475379 |
UNII | VY6S496SVX |
ChEBI | CHEBI:135458 |
ChEMBL | CHEMBL2107518 |
其他名称 | Ro 4-8347; Triengestone; 1,6-Didehydro-6-chlororetroprogesterone; 6-Chloro-9β-10α-pregna-1,4,6-triene-3,20-dione |
化学 | |
化学式 | C21H25ClO2 |
摩尔质量 | 344.879 g/mol |
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参考文献
- Dixon R, Tormey P, Darragh A. . Contraception. March 1975, 11 (3): 339–46. PMID 1116370. doi:10.1016/0010-7824(75)90042-6.
- J. Elks. . Springer. 14 November 2014: 259–. ISBN 978-1-4757-2085-3.
- Pascale Brudon. . Editions d'en bas. 1983: 93–. ISBN 978-2-8290-0039-3.
- Dr. Ian Morton; I.K. Morton; Judith M. Hall. . Springer Science & Business Media. 31 October 1999: 279–. ISBN 978-0-7514-0499-9.
- J. Horsky; J. Presl. . Springer Science & Business Media. 6 December 2012: 329–. ISBN 978-94-009-8195-9.
- . [2020-09-17]. (原始内容存档于2020-08-18).
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