5-HT4受體
配體
激動劑
- BIMU-8
- Cisapride
- ML-10302[8]
- 莫沙必利
- Prucalopride
- Renzapride
- RS-67506
- Tegaserod
- Zacopride
- Metoclopramide
- 舒必利
- RS-67333 - partial agonist
- SL65.0155 - partial agonist
- CJ-033,466 - partial agonist
拮抗劑
- Piboserod
- GR-113,808 (1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester)[9]
- GR-125,487
- RS-39604 (1-[4-Amino-5-chloro-2-(3,5-dimethoxyphenyl)methyloxy]-3-[1-[2-methylsulphonylamino]piperidin-4-yl]propan-1-one)
- SB-203,186
- SB-204,070
- ([Methoxy-11C]1-butylpiperidin-4-yl)methyl 4-amino-3-methoxybenzoate[10]
- 洋甘菊(酒精萃取)[11]
參考資料
- .
- GRCh38: Ensembl release 89: ENSG00000164270 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000026322 - Ensembl, May 2017
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- Gale JD, Grossman CJ, Whitehead JW, Oxford AW, Bunce KT, Humphrey PP. . British Journal of Pharmacology. January 1994, 111 (1): 332–8. PMC 1910004. PMID 8012715. doi:10.1111/j.1476-5381.1994.tb14064.x.
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深入閱讀
- Licht CL, 2009, Changes in the 5-HT4 receptor in animal models of depression and antidepressant treatment, PhD thesis, University of Copenhagen.
- Ullmer C, Schmuck K, Kalkman HO, Lübbert H. . FEBS Letters. August 1995, 370 (3): 215–21. PMID 7656980. doi:10.1016/0014-5793(95)00828-W.
- Blondel O, Vandecasteele G, Gastineau M, Leclerc S, Dahmoune Y, Langlois M, Fischmeister R. . FEBS Letters. August 1997, 412 (3): 465–74. PMID 9276448. doi:10.1016/S0014-5793(97)00820-X.
- Van den Wyngaert I, Gommeren W, Verhasselt P, Jurzak M, Leysen J, Luyten W, Bender E. . Journal of Neurochemistry. November 1997, 69 (5): 1810–9. PMID 9349523. doi:10.1046/j.1471-4159.1997.69051810.x.
- Claeysen S, Faye P, Sebben M, Lemaire S, Bockaert J, Dumuis A. . NeuroReport. October 1997, 8 (15): 3189–96. PMID 9351641. doi:10.1097/00001756-199710200-00002.
- Blondel O, Gastineau M, Dahmoune Y, Langlois M, Fischmeister R. . Journal of Neurochemistry. June 1998, 70 (6): 2252–61. PMID 9603189. doi:10.1046/j.1471-4159.1998.70062252.x.
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- Claeysen S, Sebben M, Becamel C, Bockaert J, Dumuis A. . Molecular Pharmacology. May 1999, 55 (5): 910–20. PMID 10220570.
- Bender E, Pindon A, van Oers I, Zhang YB, Gommeren W, Verhasselt P, Jurzak M, Leysen J, Luyten W. . Journal of Neurochemistry. February 2000, 74 (2): 478–89. PMID 10646498. doi:10.1046/j.1471-4159.2000.740478.x.
- Mialet J, Berque-Bestel I, Eftekhari P, Gastineau M, Giner M, Dahmoune Y, Donzeau-Gouge P, Hoebeke J, Langlois M, Sicsic S, Fischmeister R, Lezoualc'h F. . British Journal of Pharmacology. February 2000, 129 (4): 771–81. PMC 1571890. PMID 10683202. doi:10.1038/sj.bjp.0703101.
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外部連結
- . IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. (原始内容存档于2016-06-05).
- Human HTR4 genome location and HTR4 gene details page in the UCSC Genome Browser.
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