A20 (基因)
A20基因(或称为:肿瘤坏死因子α诱导蛋白3,英語:,缩写TNFAIP3)是人类六号染色体上的基因[4][5],可由肿瘤坏死因子α(TNF-α)诱导表达,是一种去泛素化酶和锌指蛋白,可抑制NF-κB激活和TNF介导的细胞凋亡。A20是一种非常古老的蛋白,在刺胞動物門(水母)中也有带有同源结构域的蛋白[6]。
蛋白质的相互作用
A20蛋白与下列蛋白質进行互作:TNIP1[7]、TRAF1[8][9]、TRAF2[8]、IKBKG[10]、TAX1BP1[11]、YWHAB[12]、YWHAZ[12][13]、TRAF6[9][14]和YWHAH[12][13]。
参考文献
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