足蛋白
足蛋白（、）即腎臟的組成腎元之腎小體內的鮑氏囊上之足細胞裂隙隔膜(slit diaphragm)的蛋白質成分。腎小球毛細血管內皮細胞，腎小球基底膜及裂隙隔膜充當的腎小球濾過屏障。[1] 足蛋白基因NPHS2的突變能引起腎病症候群(NS)，如局灶節段性腎小球硬化症(FSGS)或微小病變(MCD)。[2]
| 腎病2，特發性，類固醇抵抗性 (足蛋白) | |
|---|---|
| 識別 | |
| 符號 | NPHS2 |
| Entrez | 7827 |
| HUGO | 13394 |
| OMIM | 604766 |
| RefSeq | NM_014625 |
| UniProt | Q9NP85 |
| 其他資料 | |
| 基因座 | 1 q25-q31 |
註釋
- George Jarad, Jeffrey H. Miner. . Current Opinion in Nephrology and Hypertension. 2009-5, 18 (3): 226–232 [2019-02-12]. ISSN 1473-6543. （原始内容存档于2019-06-09）.
- Géraldine Mollet, Julien Ratelade, Olivia Boyer, Andrea Onetti Muda, Ludivine Morisset, Tiphaine Aguirre Lavin, David Kitzis, Margaret J. Dallman, Laurence Bugeon, Norbert Hubner, Marie-Claire Gubler, Corinne Antignac, Ernie L. Esquivel. . Journal of the American Society of Nephrology: JASN. 2009-10, 20 (10): 2181–2189 [2019-02-12]. ISSN 1533-3450. PMC 2754108. PMID 19713307. doi:10.1681/ASN.2009040379. （原始内容存档于2014-11-04）.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.