NPHS2

NPHS2，特發性，類固醇耐藥性(足細胞)
标识
代号	NPHS2; PDCN; SRN1
扩展标识	遗传学：604766 鼠基因：2157018 同源基因：22826 GeneCards: NPHS2 Gene
基因本体论描述
分子功能	· protein binding;
细胞成分	· endoplasmic reticulum; · plasma membrane; · integral component of plasma membrane; · cell-cell junction; · intrinsic component of the cytoplasmic side of the plasma membrane; · slit diaphragm; · protein complex; · membrane raft; · extracellular vesicular exosome;
生物过程	· excretion; · actin cytoskeleton reorganization; · metanephric glomerular visceral epithelial cell development;
	Sources: Amigo / QuickGO
RNA表达模式
	更多表达数据
直系同源体

足蛋白(、NPHS2)是在人體內由NPHS2(Nephrosis 2)基因編碼的蛋白質。[1][2][3]

交互作用

NPHS2已經顯示出與腎病蛋白(Nephrin)[4]及CD2AP[4]有所交互作用。

參見

局灶節段性腎小球硬化症

註釋

Fuchshuber A, Jean G, Gribouval O, Gubler MC, Broyer M, Beckmann JS, Niaudet P, Antignac C. . Hum Mol Genet. Mar 1996, 4 (11): 2155–8. PMID 8589695. doi:10.1093/hmg/4.11.2155.
Boute N, Gribouval O, Roselli S, Benessy F, Lee H, Fuchshuber A, Dahan K, Gubler MC, Niaudet P, Antignac C. . Nat Genet. May 2000, 24 (4): 349–54. PMID 10742096. doi:10.1038/74166.
. （原始内容存档于2019-10-18）.
Schwarz, K; Simons M; Reiser J; Saleem M A; Faul C; Kriz W; Shaw A S; Holzman L B; Mundel P. . J. Clin. Invest. (United States). Dec 2001, 108 (11): 1621–9. ISSN 0021-9738. PMC 200981. PMID 11733557. doi:10.1172/JCI12849.

延伸閱讀

Caridi G, Perfumo F, Ghiggeri GM. . Pediatr. Res. 2005, 57 (5 Pt 2): 54R–61R. PMID 15817495. doi:10.1203/01.PDR.0000160446.01907.B1.
. Nature Genetics. 2000, 25 (1): 125. PMID 10802674. doi:10.1038/75526.
Huber TB, Kottgen M, Schilling B; 等. . J. Biol. Chem. 2001, 276 (45): 41543–6. PMID 11562357. doi:10.1074/jbc.C100452200.
Caridi G, Bertelli R, Carrea A; 等. . J. Am. Soc. Nephrol. 2002, 12 (12): 2742–6. PMID 11729243.
Schwarz K, Simons M, Reiser J; 等. . J. Clin. Invest. 2002, 108 (11): 1621–9. PMC 200981. PMID 11733557. doi:10.1172/JCI12849.
Karle SM, Uetz B, Ronner V; 等. . J. Am. Soc. Nephrol. 2002, 13 (2): 388–93. PMID 11805166.
Koziell A, Grech V, Hussain S; 等. . Hum. Mol. Genet. 2002, 11 (4): 379–88. PMID 11854170. doi:10.1093/hmg/11.4.379.
Boute N, Roselli S, Gribouval O; 等. . Néphrologie. 2002, 23 (1): 35–6. PMID 11908478.
Carraro M, Caridi G, Bruschi M; 等. . J. Am. Soc. Nephrol. 2002, 13 (7): 1946–52. PMID 12089392. doi:10.1097/01.ASN.0000016445.29513.AB.
Saleem MA, Ni L, Witherden I; 等. . Am. J. Pathol. 2002, 161 (4): 1459–66. PMC 1867300. PMID 12368218. doi:10.1016/S0002-9440(10)64421-5.
Sellin L, Huber TB, Gerke P; 等. . FASEB J. 2003, 17 (1): 115–7. PMID 12424224. doi:10.1096/fj.02-0242fje.
Tsukaguchi H, Sudhakar A, Le TC; 等. . J. Clin. Invest. 2003, 110 (11): 1659–66. PMC 151634. PMID 12464671. doi:10.1172/JCI16242.
Strausberg RL, Feingold EA, Grouse LH; 等. . Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241. PMID 12477932. doi:10.1073/pnas.242603899.
Komatsuda A, Wakui H, Maki N; 等. . Renal failure. 2003, 25 (1): 87–93. PMID 12617336. doi:10.1081/JDI-120017471.
Ohashi T, Uchida K, Uchida S; 等. . Histochem. Cell Biol. 2004, 119 (3): 257–64. PMID 12649741. doi:10.1007/s00418-003-0511-x.
Maruyama K, Iijima K, Ikeda M; 等. . Pediatr. Nephrol. 2004, 18 (5): 412–6. PMID 12687458. doi:10.1007/s00467-003-1120-6.
Caridi G, Bertelli R, Di Duca M; 等. . J. Am. Soc. Nephrol. 2003, 14 (5): 1278–86. PMID 12707396. doi:10.1097/01.ASN.0000060578.79050.E0.
Guan N, Ding J, Zhang J, Yang J. . Pediatr. Nephrol. 2004, 18 (11): 1122–7. PMID 12961083. doi:10.1007/s00467-003-1240-z.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[pmid8589695-1] Fuchshuber A, Jean G, Gribouval O, Gubler MC, Broyer M, Beckmann JS, Niaudet P, Antignac C. . Hum Mol Genet. Mar 1996, 4 (11): 2155–8. PMID 8589695. doi:10.1093/hmg/4.11.2155.

[pmid10742096-2] Boute N, Gribouval O, Roselli S, Benessy F, Lee H, Fuchshuber A, Dahan K, Gubler MC, Niaudet P, Antignac C. . Nat Genet. May 2000, 24 (4): 349–54. PMID 10742096. doi:10.1038/74166.

[3] . （原始内容存档于2019-10-18）.

[pmid11733557-4] Schwarz, K; Simons M; Reiser J; Saleem M A; Faul C; Kriz W; Shaw A S; Holzman L B; Mundel P. . J. Clin. Invest. (United States). Dec 2001, 108 (11): 1621–9. ISSN 0021-9738. PMC 200981. PMID 11733557. doi:10.1172/JCI12849.