香柑内酯

**香柑内酯**
系统（IUPAC）命名名称
	5-methoxy-2H-furo[3,2-g]chromen-2-one
临床数据
给药途径	口服
合法狀態
合法状态	处方药（℞-only）;
识别
CAS注册号	484-20-8
ATC代码	D05BA03
PubChem	CID 2355
ChemSpider	2265
UNII	4FVK84C92X
KEGG	D07521
ChEMBL	CHEMBL24171
化学
化学式	C12H8O4
摩尔质量	216.19 g/mol
	SMILES O=C\1Oc3c(/C=C/1)c(OC)c2ccoc2c3;
	InChI InChI=1S/C12H8O4/c1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h2-6H,1H3 ; Key:BGEBZHIAGXMEMV-UHFFFAOYSA-N ;

香柑内酯（5-甲氧补骨脂素）是一种存在于香柠檬精油与其他柑橘属植物精油，[1] 以及葡萄柚汁的呋喃香豆素（furanocoumarin），属补骨脂素的衍生物。[2] 它是香柠檬精油中引起光敏性（光毒性）的活性物质。[3] 目前市面上的香水采用的是不含香柑内酯的香柠檬精油或人工合成的类似香味物质。

医学上香柑内酯与长波紫外线（UVA）一同用于银屑病的長波紫外線光化治療。[4][5]

参考资料

Calvarano I., Calvarano M., Gionfriddo F., Bovalo F., Postorino E. . Essenze Derivati agrumari. 1995, 65: 488–502.
Sakamaki N., Nakazato M., Matsumoto H., Hagino K., Hirata K., Ushiyama H. . Journal of the Food Hygienic Society of Japan. 2008, 49 (4): 326–331. PMID 18787320. doi:10.3358/shokueishi.49.326.
Francesco Gionfriddo, Enrico Postorino and Giuseppe Calabrò. . Perfumer & Flavorist. 2004, 29.
HONIGSMANN, HERBERT; JASCHKE, ERNA; GSCHNAIT, FRITZ; BRENNER, WILHELM; FRITSCH, PETER; WOLFF, KLAUS. . British Journal of Dermatology (Wiley-Blackwell). 1979, 101 (4): 369–378. ISSN 0007-0963. doi:10.1111/j.1365-2133.1979.tb00014.x.
A. Tanew, B. Ortel, K. Rappersberger, H. Hönigsmann. . Journal of the American Academy of Dermatology. 1988-2, 18 (2 Pt 1): 333–338 [2019-05-25]. ISSN 0190-9622. PMID 3279089. 请检查|date=中的日期值 (帮助)

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[1] Calvarano I., Calvarano M., Gionfriddo F., Bovalo F., Postorino E. . Essenze Derivati agrumari. 1995, 65: 488–502.

[2] Sakamaki N., Nakazato M., Matsumoto H., Hagino K., Hirata K., Ushiyama H. . Journal of the Food Hygienic Society of Japan. 2008, 49 (4): 326–331. PMID 18787320. doi:10.3358/shokueishi.49.326.

[3] Francesco Gionfriddo, Enrico Postorino and Giuseppe Calabrò. . Perfumer & Flavorist. 2004, 29.

[4] HONIGSMANN, HERBERT; JASCHKE, ERNA; GSCHNAIT, FRITZ; BRENNER, WILHELM; FRITSCH, PETER; WOLFF, KLAUS. . British Journal of Dermatology (Wiley-Blackwell). 1979, 101 (4): 369–378. ISSN 0007-0963. doi:10.1111/j.1365-2133.1979.tb00014.x.

[5] A. Tanew, B. Ortel, K. Rappersberger, H. Hönigsmann. . Journal of the American Academy of Dermatology. 1988-2, 18 (2 Pt 1): 333–338 [2019-05-25]. ISSN 0190-9622. PMID 3279089. 请检查|date=中的日期值 (帮助)